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Table 5 Results by Autonomous Region

From: Budgetary impact analysis of buprenorphine-naloxone combination (Suboxone®) in Spain

Region Eligible population Scenario without B/N combination Budget impact (€) Scenario with B/N combination Budget impact (€) Difference (€) with B/N vs. without B/N
   1 st 2 nd 3 rd 1 st 2 nd 3 rd 1 st 2 nd 3 rd
Andalucia 17,637 19,440,146 18,100,409 17,937,671 19,626,710 18,223,440 18,067,201 186,563 123,031 129,530
Aragon 1,362 1,501,246 1,397,786 1,385,219 1,515,653 1,407,287 1,395,222 14,407 9,501 10,003
Asturias 3,289 3,625,256 3,375,418 3,345,070 3,660,047 3,398,361 3,369,225 34,791 22,943 24,155
Baleares 2,541 2,800,783 2,607,764 2,584,318 2,827,662 2,625,490 2,602,980 26,879 17,725 18,662
Canary Islands 5,063 5,580,624 5,196,029 5,149,313 5,634,180 5,231,348 5,186,497 53,556 35,318 37,184
Cantabria 795 876,278 815,888 808,553 884,688 821,434 814,392 8,409 5,546 5,839
Castilla La Mancha 2,226 2,453,579 2,284,488 2,263,948 2,447,125 2,300,016 2,280,297 23,547 15,528 16,348
Castilla León 4,197 4,626,087 4,307,275 4,268,549 4,670,483 4,336,553 4,299,373 44,396 29,277 30,824
Catalonia 7,922 8,731,918 8,130,149 8,057,052 8,815,717 8,185,411 8,115,233 83,799 55,262 58,181
Extremadura 1,683 1,855,064 1,727,221 1,711,691 1,872,867 1,738,961 1,724,052 17,803 11,740 12,360
Galicia 7,822 8,621,694 8,027,522 7,955,347 8,704,435 8,082,086 8,012,794 82,741 54,564 57,447
Madrid 9,606 10,588,084 9,858,396 9,769,761 10,689,696 9,925,405 9,840,309 101,612 67,009 70,549
Murcia 2,021 2,227,620 2,074,101 2,055,453 2,248,998 2,088,199 2,070,296 21,378 14,098 14,843
Navarra 799 880,687 819,994 812,621 889,139 825,567 818,489 8,452 5,574 5,868
Basque Country 2,633 2,902,189 2,702,182 2,677,887 2,930,041 2,720,549 2,697,224 27,852 18,367 19,337
La Rioja 762 839,904 782,021 774,990 847,965 787,337 780,587 8,060 5,315 5,596
Valencia 6,425 7,081,870 6,593,816 6,534,532 7,149,833 6,638,635 6,581,718 67,963 44,819 47,187
Ceuta 603 664,649 618,844 613,280 671,027 623,050 617,708 6,379 4,206 4,429
Melilla 425 468,451 436,167 432,245 472,946 439,131 435,367 4,496 2,965 3,121
  1. Total cost of AOT per patient was estimated at €1,102; €1,026 and €1,017 for the first, second and third year, respectively, in the scenario without B/N combination. Incremental total cost per patient comparing the inclusion of the B/N combination to the scenario where methadone was the only medication available, was €10.58, €6.98 and €7.34 in the first, second and third year, respectively. National budgetary impact by target population group for the 3 study years is shown in Table 4.