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Table 6 Results of one-way sensitivity analyses.

From: Budgetary impact analysis of buprenorphine-naloxone combination (Suboxone®) in Spain

Parameter modified Value in BC Value in SA Scenario without B/N combination Scenario with B/N combination Difference (€) with B/N vs. without B/N
    1 st year 2 nd year 3 rd year 1 st year 2 nd year 3 rd year 1 st year 2 nd year 3 rd year
Transition probabilities See table 1 Same values for B/N combination than used for methadone 1,102 1,026 1,017 1,113 1,035 1,028 10.58 9.18 11.13
B/N combination uptakes 10%, 15% and 20% for 1st, 2nd and 3rd year 0.97%; 2.57% and 3.83% for 1st, 2nd and 3rd year 1,102 1,026 1,017 1,103 1,028 1,019 1.03 1.37 1.58
Initial proportion of patient distribution HTP: 30% and LITP: 70% HTP: 100% 1,477 1,185 1,127 1,513 1,204 1,144 35.260 19.13 16.46
   LITP: 100% 941 958 970 941 960 973 0 1.76 3.44
Resource cost (cost per minute) See table 3 +10% 1,201 1,126 1,116 1,218 1,129 1,119 7.78 2.87 2.30
   -10% 995 926 918 1,008 937 930 13.38 11.08 12.39
  1. Yearly budgetary impact per patient (€, 2010)
  2. BC: Base Case; SA: Sensitivity analysis