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Table 2 Inputs: Treatment effectiveness profiles

From: Treatment of type 2 diabetes with saxagliptin: a pharmacoeconomic evaluation in Argentina

Parameter

SAXA + MET

SU + MET

Reference

Insulin

Reference

HbA 1c

     

Reduction in year 1 (%)

−0.57 (0.041)

−0.66 (0.041)

[23]

−1.0

Assumed

Delay in creep (years)

3.00

0.00

[25–28]

0.00

[25–28]

Body weight (kg)

−1,100 (0.017)

1,100 (0.018)

[23]

2,500

[24]

Adverse Effect

     

Hypoglycemic events

     

Number of symptomatic events

0.04 (0.02)

1.73 (0.08)

[23]

10.00

Assumed

Probability of seriousness

0.00

0.02

[23]

0.02

[24]

Discontinuation probability

0.00

0.00

Assumed

0.00

Assumed

  1. Standard deviation (SD) in parentheses.