Table 3 Inputs: Costs data

Treatment

MET + SU (yearly)

217.99 *

-

-

-

MET * SAXA (yearly)

844.38 *

-

-

-

Insulin (yearly)

1,001.06*

-

-

-

Adverse effect

Profound hypoglycemia

147.70**

Gamma

50

500

Symptomatic and nocturnal hypoglycemia

0.00 ^Δ

-

-

-

Macrovascular events

Ischemic heart disease

Fatal/nonfatal

1,204.2^†

Gamma

500

4,500

Maintenance

228.8‡

Gamma

100

500

Myocardial infarction

Fatal/nonfatal

1,548.1^†

Gamma

500

4,500

Maintenance

294.1‡

Gamma

100

500

Congestive heart failure

Fatal/nonfatal

719.9^†

Gamma

500

4,500

Maintenance

136.8‡

Gamma

100

500

Stroke

Fatal/nonfatal

942.4^†

Gamma

500

4,500

Maintenance

179.1‡

Gamma

100

500

Microvascular events

Amputation

Fatal/nonfatal

789.3^†

Gamma

500

4,500

Maintenance

149.9‡

Gamma

100

500

Blindness

Fatal/nonfatal

390.4^†

Gamma

200

2,000

Maintenance

74.2‡

Gamma

50

500

ESRD

Fatal/nonfatal

13,759.2^†

Gamma

10,000

30,000

Maintenance

13,759.2^†

Gamma

10,000

30,000