Table 6 Nationwide annual cost of managing HAE episodes with icatibant (Euros)
Most favourable scenario | Least favourable scenario | |||||||
|---|---|---|---|---|---|---|---|---|
Variable | Strategy 1 (€) | Strategy 2 (€) | Savings (€) | Savings (%) | Strategy 1 (€) | Strategy 2 (€) | Savings (€) | Savings (%) |
Direct costs | 21,819,956 | 20,194,340 | 1,625,616 | 7.45 | 1,121,218 | 1,048,929 | 72,289 | 6.45 |
Medical | 21,655,858 | 20,177,846 | 1,478,012 | 6.82 | 1,116,431 | 1,047,707 | 68,723 | 6.16 |
Icatibant | 20,025,875 | 20,025,875 | 0 | 0.00 | 1,024,811 | 1,024,811 | 0 | 0.00 |
Visits* | 1,559,016 | 150,900 | 1,408,116 | 90.32 | 90,390 | 22,808 | 67,581 | 74.77 |
Admissions | 66,974 | 938 | 66,037 | 98.60 | 929 | 58 | 871 | 93.78 |
Tracheotomy | 3,992 | 133 | 3,859 | 96.67 | 301 | 30 | 271 | 90.00 |
Non-medical | 164,099 | 16,494 | 147,604 | 89.95 | 4,787 | 1,222 | 3,565 | 74.47 |
Transportation | 164,099 | 16,494 | 147,604 | 89.95 | 4,787 | 1,222 | 3,565 | 74.47 |
Indirect costs | 873,371 | 183,627 | 689,743 | 78.97 | 28,643 | 10,613 | 18,030 | 62.95 |
Caretaker | 280,398 | 88,246 | 192,152 | 68.53 | 9,800 | 3,964 | 5,837 | 59.55 |
Labor loss | 258,830 | 84,243 | 174,587 | 67.45 | 10,445 | 4,130 | 6,315 | 60.46 |
Death | 334,142 | 11,138 | 323,004 | 96.67 | 8,398 | 2,519 | 5,878 | 70.00 |
Social costs | 22,693,327 | 20,377,967 | 2,315,360 | 10.20 | 1,149,861 | 1,059,542 | 90,319 | 7.85 |