From: Will vaccination against rotavirus infection with RIX4414 be cost-saving in Germany?
Variable | Distribution type | Mean | Source |
---|---|---|---|
Average number of days staying at home after consultation visit | General (2,3,4,5,6,7; 0.05,0.05,0.15,0.2,0.3,0.25) | 5.2 | [11] |
Average number of days staying at home due to hospitalisation | General (2,3,4,5,6,7; 0.05,0.02,0.02,0.25,0.25,0.05) | 4.6 | [56] |
Average number of days staying at home due to nosocomial rotavirus infection | Gamma (2,1) | 2 | [26] |
Proportion of families with both parents working | Normal (0.31, 0.031; truncated 0.1,0.55) | 31% | [47] |
Proportion seeking medical advice | Beta general (6.5,7; 0.65,0.9) | 77% | [1] |
Probability of hospitalisation | Beta general (10,5; 0.17,0.26) | 23% | [9] |
Probability of nosocomial infection in the first year | Beta general (6,4; 0.01,0.048) | 3.28% | |
Vaccine efficacy for mild RVGE, 1 year, 1 dose | Normal (0.784; 0.03) | 0.784 | |
Vaccine efficacy for moderate RVGE, 1 year, 1 dose | Normal (0.808; 0.03) | 0.808 | |
Vaccine efficacy for severe RVGE, 1 year, 1 dose | Normal (0.900; 0.03) | 0.900 | |
Vaccine efficacy for mild RVGE, 1 year, 2 doses | Normal (0.871; 0.03) | 0.871 | |
Vaccine efficacy for moderate RVGE, 1 year, 2 doses | Normal (0.898; 0.03) | 0.898 | |
Vaccine efficacy for severe RVGE, 1 year, 2 doses | Normal (1.000; 0.1; truncated (0.871; 1) | 0.94 | |
Age-specific incidence rate of diarrhoea | Normal (0.023; 0.0023) | 0.023 | |
Vaccine coverage rate | Uniform (0.75;1) | 87.5% | |
Discount rate on cost | Discrete (0,0.75,1,1.5) | 3% |