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Table 2 Results of the reviewed studies

From: Genome sequencing: a systematic review of health economic evidence

  Author (publication year) Throughput Mb/day Bases/read Raw accuracy Cost per instrument Cost per Mb approximately
Sanger Kircher et al. (2010) 6 800 0.99991 - $500.00
Roche/454 GS FLX Titanium Shendure et al. (2008) - 250 - $500 000 $60.00
Tucker et al. (2009) 1 200 400 0.99 - $84.40
Kircher et al. (2010) 750 400 0.9991 - $20.00
Glenn (2011) - 400 0.99 - $12.40
Pareek et al. (2011) 1 000 400 0.995 $500 000 $84.39
Illumina Genome Analyzer II/IIx Tucker et al. (2009) 2 500 75+ 0.985 - $6.00
Kircher et al. (2010) 5 000 100 0.991 - $0.50
Illumina Solexa Shendure et al. (2008) - 36 - $430 000 $2.00
Pareek et al. (2011) 1 500 36 0.985 $400 000 $5.97
Illumina HiSeq 2000 Glenn (2011) - 100 + 100 0.99 - $0.10
Applied Biosystems SOLiD 4 Shendure et al. (2008) - 35 - $591 000 $2.00
Pareek et al. (2011) 1 850 35 0.9994 $525 000 $5.81
Tucker et al. (2009) 2 500 50 0.994 - $5.80
Kircher et al. (2010) 5 000 50 0.991 - $0.50
Life Technologies SOLiD 5500 Glenn (2011) - 75 + 35 0.99 - <$0.08
Life Technologies SOLiD 5500xl Glenn (2011) - 75 + 35 0.99 - <$0.07
Helicos HeliScope Shendure et al. (2008) - 30 - $1 350 000 $1.00
Tucker et al. (2009) 3 100 30-35 0.99 - -
Kircher et al. (2010) 5 000 32 0.99 - $0.50
Glenn (2011) - 35 - - -
Pareek et al. (2011) 2 500 >1000 >0.99 - -
Polonator Shendure et al. (2008) - 13 - $155 000 $1.00