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Table 4 Drug and resource costs by country

From: A comparison of the cost-effectiveness of treatment of prolonged acute convulsive epileptic seizures in children across Europe

 

Scotland

Wales

Germany

Spain

France

Italy

Switzerland

Reference year

2012–2013

2012–2013

2012–2013

2012–2013

2011–2012

2012

2012

Cost elements

Ambulance cost

€317.23

€284.68

€0.00 a

€309.36

€1,120.76

€113.27

€1,217.06

A&E: admitted patients

€141.35

€141.35

€542.87

€129.23

–

€335.12

–

A&E: non-admitted patients

€113.41

€113.41

€542.87

€111.10

€25.32

€335.12

€6,194.85

Inpatient admission

€680.16

€680.16

€403.00

€1,616.89

€1,436.21

€1,147.75

€6,194.85

ICU admission

€1,574.28

€1,574.28

€1,115.00

€2,254.91

€8,980.05

€4,322.30

€15,157.31

Drug costs (per dose)

 

  BUCCOLAM b

€26.97 c

€26.97 c

€28.54

€17.38

€17.17

€22.65

€39.93 d

  Rectal diazepam

€2.24

€2.24

€5.08

€0.94

€0.53

€0.00 e

€5.27

  Unlicensed buccal midazolam

€30.38 f

€30.66g

–

–

–

–

–

  Phenytoin

–

–

€6.60

–

€0.06

–

–

  Oral clonazepam

–

–

–

–

€0.08

–

–

  IV clonazepam

–

–

€1.70

–

€0.79

–

€5.29

  Lorazepam tablets

–

–

€0.39

–

–

–

€0.55

  IV midazolam

–

–

–

–

–

€4.18

–

  Intranasal midazolam

–

–

–

–

–

–

€36.51

  Chloral hydrate

–

–

–

–

–

–

€1.40

  Phenobarbital

–

–

–

–

–

–

€82.78

  IV diazepam

–

–

–

–

–

–

€7.20

  IV lorazepam

–

–

–

–

–

–

€2.40

  1. A&E = accident and emergency; ICU = intensive care unit; IV = intravenous.
  2. a Ambulance costs for Germany set to zero as they are included in aggregated A&E costs; b The drug costs used for BUCCOLAM were defined by local HTA body requirements (e.g. ex factory, public price) and include VAT as appropriate, therefore are not comparable between countries; c The drug cost used represents an average of each of the four strengths available; d At the time of publication, the approved price for BUCCOLAM in this country has not been agreed – the price shown is the maximum price allowable under the price referencing rules in Switzerland.
  3. e Italian cost of rectal diazepam is zero as this drug is not reimbursed by the Italian national health service; f Based on May 2013 Drug Tariff [20]; g Based on May 2013 Drug Tariff price plus a sourcing fee for medicines classed as ‘specials’ [21, 22].
  4. All costs are presented in Euros, converted on 30/10/12, using the following rates from xe.com currency converter: 1 Euro (EUR) = 0.806579 British Pound (GBP), 0.82165 Swiss Francs (CHF).
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Health Economics Review

ISSN: 2191-1991

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