Table 5 Utility values and event durations used to calculate QALYs lost to seizures
Utility values | Scotland | Wales | Germany | Spain | France | Italy | Switzerland |
|---|---|---|---|---|---|---|---|
Proportion of patients with severe disability | 10% | 20% | 20% | 10% | 46% | 50% | 17.5% |
Quality of life for patients without severe disabilities | |||||||
Baseline | 0.879 | 0.920 | 0.920 | 0.879 | 0.879 | 0.920 | 0.864 |
During seizure | −0.204 | −0.334 | −0.334 | −0.204 | −0.436 | −0.334 | −0.436 |
Following seizure – no ambulance | 0.722 | 0.722 | 0.722 | 0.722 | 0.507 | 0.722 | 0.358 |
Following seizure –ambulance called | 0.100 | 0.100 | 0.100 | 0.100 | 0.413 | 0.100 | 0.336 |
Quality of life for patients with severe disabilities | |||||||
Baseline | −0.127 | −0.127 | −0.127 | −0.127 | −0.001 | −0.127 | −0.127 |
During seizure | −0.359 | −0.359 | −0.359 | −0.359 | −0.516 | −0.359 | −0.594 |
Following seizure – no ambulance | −0.313 | −0.313 | −0.313 | −0.313 | −0.230 | −0.313 | −0.313 |
Following seizure – ambulance called | −0.313 | −0.313 | −0.313 | −0.313 | −0.216 | −0.313 | −0.313 |
Event timings | |||||||
Average duration of seizure (minutes) | BUCCOLAM 8; Current care 8 | BUCCOLAM 8; Current care 8.35 | BUCCOLAM 8; Current care 15 | BUCCOLAM 8; Current care 15 | BUCCOLAM 8; Current care 15 | BUCCOLAM 8; Current care 15 | BUCCOLAM 8; Current care 15 |
Time to recovery (hours) – where available, the duration of the postictal phase is shown in parentheses | |||||||
No ambulance | 21.0 | 24.0 (4.0) | 0.9 (0.6) | 21.0 | 1.25 (0.2) | 21.0 | BUCCOLAM 1.25; Current care 1.24 (0.2) |
Ambulance but no hospitalisation | 40.5 | 30.0 (4.0) | 3.0 (1.0) | 40.5 | 2.0 (0.6) | 40.5 | BUCCOLAM 2.00; Current care 1.98 (0.6) |
Ambulance and hospitalisation | 64.5 | 96.0 (14.0) | 6.0 (2.5) | 64.5 | 12.5 (0.6) | 112.5 | BUCCOLAM 12.50; Current care 12.48 (0.6) |
Ambulance and hospitalisation in intensive care unit | 88.5 | 120.0 (24.0) | 6.0 (2.5) | 88.5 | 12.5 (0.6) | 136.5 | BUCCOLAM 12.50; Current care 12.48 (0.6) |