Table 4 Impact of generic substitution and reference pricing on the daily cost of quetiapine in Finland

Level before generic substitution and reference pricing (β₀)

6.0130

5.8591, 6.1669

<0.0001

Trend before generic substitution and reference pricing (β₁)

−0.0248

−0.0311, −0.0185

<0.0001

Level change after generic substitution and reference pricing (β₂)

−1.0493

−1.1634, −0.9352

<0.0001

Trend change after generic substitution and reference pricing (β₃)

−0.0506

−0.0757, −0.0254

0.0002