Table 5 Impact of generic substitution and reference pricing on the daily cost of risperidone in Finland

Level before generic substitution (β₀)

6.2567

6.1842, 6.3292

<0.0001

Trend before generic substitution (β₁)

0.0226

0.0178, 0.0274

<0.0001

Pre-effect to generic substitution (β₂)

−1.4291

−1.5947, −1.2635

<0.0001

Level change after generic substitution (β₃)

−1.3164

−1.4068, −1.2260

<0.0001

Trend change after generic substitution (β₄)

−0.0407

−0.0497, −0.0317

<0.0001

Level change after reference pricing (β₅)

−0.7895

−0.9001, −0.6789

<0.0001