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Table 2 Direct and non-direct costs variability intra country by patient (€ 2010)

From: Economic impact of HIV/AIDS: a systematic review in five European countries

  Spain (n* = 9**) Germany (n* = 3) France (n* = 4**) Italy (n* = 17**) United Kingdom (n* = 15**)
n MEAN SD MIN MAX n MEAN SD MIN MAX n MEAN SD MIN MAX n MEAN SD MIN MAX n MEAN SD MIN MAX
Healthcare costs
Antiretrovirals 9 10.248,37 4.489,01 5.883,34 20.276,09 3 18.182,24 1.132,91 17.424,92 19.317,96 4 13.152,19 3.177,05 671,51 13.974,88 17 6.579,60 3.252,27 1.185,66 9.974,46 15 16.820,15 7.475,57 7.143,75 29.065,71
Other drugs 3 202,40 146,39 86,10 367,11 3 5.931,71 2.222,07 4.283,57 8.153,47 1 961,37 - - - 5 5.304,43 1.953,96 988,24 7.054,24 0 - - - -
Hospitalization 6 985,68 997,51 31,09 2.621,26 3 6.258,58 3.058,57 3.980,94 9.316,08 2 1.629,00 298,80 1.575,33 2.460,77 11 1.178,43 884,20 67,17 3.966,24 9 7.241,7 6.249,54 1.884,59 21.275,59
Primary care 6 378,85 195,62 261,23 871,22 3 488,02 249,56 231,87 719,55 4 2.468,54 820,62 182,84 5.860,8 9 155,18 254,24 31,22 1.571,93 0 - - - -
Acute care 6 97,29 52,19 52,61 211,45 0 - - - - 0 - - - - 0 - - - - 0 - - - -
Diagnostic tests 3 885,13 135,76 771,29 1.021,21 3 1.263,22 171,72 1.057,01 1.396,65 0 - - - - 4 1.375,87 74,90 1.341,49 1.530,34 0 - - - -
Other direct costs 2 33,24 50,66 4,78 78,33 3 104,41 26,23 84,91 130,63 1 4.099,84 - - - 10 713,93 1.160,36 230,55 10.111,36 9 7.060,13 4.384,84 3.245,49 13.052,02
Total heatlhcare costs *** 9 11.638,38 3.756,36 8.547,53 20.276,09 3 32.109,62 6.960,48 26.650,64 39.041,96 4 14.821,02 1.896,73 5.380,25 15.210,43 17 6.399,23 2.503,00 2.173,90 25.944,39 15 25.339,7 14.548,79 10.571,45 53.241,22
Non-healthcare costs
Occupational losses 3 5.661,18 1.871,58 4.045,37 7.152,04 0 - - - - 0 - - - - 3 1.353,56 609,90 788,55 1.986,69 6 5.613,33 4.564,90 1.722,51 11.962,60
Formal care 0 - - - - 0 - - - - 0 - - - - 0 - - - - 6 1.909,99 628,43 1.259,27 2.683,22
Informal care 0 - - - - 0 - - - - 0 - - - - 0 - - - - 6 1.816,30 531,32 1.451,24 2.588,28
Other non-direct costs 0 - - - - 0 - - - - 0 - - - - 0 - - - - 6 1.007,62 2.445,77 0 23.751,13
Total non-healthcare costs 3 5.661,18 1.871,58 4.045,37 7.152,04 0 - - - - 0 - - - - 3 1.353,56 609,90 788,55 1.986,69 6 10.347,24 7.448,33 4.443,02 23.751,13
  1. * = number of cost estimates included in the analysis;** = In France, Spain, Italy and United Kingdom, we found 22 cost estimates, originated by 8 different studies, that: (a) did not have similar methodology than the rest of studies, so, there were indicen studies (when most part of the studies were prevalence studies); and, (b) did not incorporate antiretrovirals costs and another type of cost (so, these studies either incorporate antirretroviral costs or any other type of cost). For this reason, authors decided to include in this comparative intra country analysis with only 61 estimates and do not incorporate studies such as Domingo et al. (1998), Evans et al. (2009), Floridia et al. (2000), Llibre-Codina et al. (2007), Mompó et al. (2000), Rahmouni et al. (1998), Sculpher et al. (1998) and, Yazdanpanah et al. (2002); and, *** Total healthcare costs are not equal to the summ of means of each different type of costs due to: (i) not all the different types of specified costs in this list were included in the different studies; and, y (ii) the average cost has been weighted by the sample size for each study.