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Table 1 Basic parameters

From: Costing of diabetes mellitus type II in Cambodia

Parameter

Explanation

Value

Source

p_death_rest

non-T2DM mortality

age-specific

[27]

p_T2DM

age-specific incidence of T2DM

age-specific

[28]

p_Diagnosis_late

probability of clinical diagnosis with persisting complications

0.2

Assumption

p_Diagnose_early

probability of clinical diagnosis without complications or in the first year after development of complications

0.08

Assumption

p_OAD

probability of change of therapy to OAD-therapy

0.98

Assumption

p_Insulin

probability of change of therapy to OAD/insulin or mono-insulin

0.04

[29]

p_Insulin_Adherence

share of patients taking insulin in those requiring it

0.125

[30]

p_OAD_Adherence

share of patients taking OAD medication in those requiring it

0.125

[30]

p_stroke_death

stroke-related mortality

0.38136

[31]

p_MI_death

myocardial infarction-related mortality

0.7068

[31]

p_nephro

incidence diabetic nephropathy

0.01479

[32]

p_retino

incidence diabetic retinopathy

0.02124

[33]

p_neuro

incidence distal symmetric neuropathy

0.04658

[34]

p_Angina

incidence angina pectoris

0.00668

[31]

p_PVD

incidence PVD

0.00847

[35]

p_MI

incidence myocardial infarction

0.01735

[31]

p_stroke

incidence stroke

0.00529

[31]

p_heartfailure

incidence heart failure

0.00329

[31]

c_Diagnosis

unit cost FPG-test

1.00 USD

[36]

c_ambulatory

Annual cost outpatient treatment

2.66 USD

[36],[37]

c_Laboratory

Annual cost laboratory exams

1.28 USD

[36],[38]

c_OAD

Annual average cost for OAD medication

24.85 USD

[36],[38],[39]

c_Insulin

Annual average cost for insulin therapy (weighted mean for monotherapy and insulin-OAD-combined therapy)

114.26 USD

[36],[38],[39]

c_Hospital

Annual average cost for inpatient treatment

35.89 USD

[40]

  1. *adjusted.