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Table 3 Cost-effectiveness results (cohort of 1,000 patients)

From: Cost effectiveness of lanthanum carbonate in chronic kidney disease patients in Spain before and during dialysis

 

Continuous CB

Second line LC

Difference

Therapy response

Number of responders in predialysis

445

658

213

Number of responders in dialysis

−60

−57

3

Total number of responders

385

601

216

Health outcomes

Life Years

6,868

6,981

113

Dialysis free years

0

108

108

QALY’s

4,579

4,653

74

Costs –(€, 2013)

Total costs (€ thousand)

€5,044

€1,169

€ -3,875

Drug costs (€ thousand)

€468

€1,169

€ 701

Dialysis costs (€ thousand)

€4,576

€0

 

Cost-effectiveness incremental ratio (ICER)

Cost per life-year gained (€)

Dominant

Cost per QALY gained (€)

Dominant

Net monetary benefit (€ thousand)

€6,092

  1. CA: Calcium Acetate; CB: Calcium Binder; CC: Calcium Carbonate; ICER: Incremental cost-effectiveness ratio; LC: Lanthanum Carbonate; QALY: Quality Adjusted Life Year.
  2. Detailed results in terms of total costs and health benefits obtained for 1,000 patients followed lifetime, with each of the comparators are shown. Differences between therapeutic alternatives were calculated to estimate ICER. LC resulted a dominant strategy (more efficacious and less costly) compared to CB.