Table 4 One-way sensitivity analysis
Continuous CB | Second line LC | Difference | ICER (€/QALY gained) | ||
|---|---|---|---|---|---|
BASE CASE | |||||
QALYs | 4,579 | 4,653 | 73.88 | Dominant | |
Costs (thousands) | €5,044 | 1,169 | - €3,875 | ||
SA1 | Time horizon (5 years) | ||||
QALYs | 2,555 | 2,580 | 25.50 | Dominant | |
Costs (€ thousand) | €2,452 | €835 | - €1,616 | ||
SA2 | Time horizon (10 years) | ||||
QALYs | 3,711 | 3,760 | 48.67 | Dominant | |
Costs (€ thousand) | €3,920 | €1,028 | - €2,892 | ||
SA3 | Included unrelated future dialysis costs | ||||
QALYs | 4,579 | 4,653 | 73.88 | €45,557 | |
Costs (€ thousand) | €127,149 | €130,515 | €3,336 | ||
SA4 | Dialysis target level 5 mg/dL | ||||
QALYs | 4,579 | 4,658 | 79.30 | Dominant | |
Costs (€ thousand) | €5,044 | €1,383 | - €3,661 | ||
S5 | Annual Discount Rate (6%) | ||||
QALYs | 3,846 | 3,903 | 56.95 | Dominant | |
Costs (€ thousand) | €4,122 | €1,036 | - €3,086 | ||
S6 | Annual Discount Rate (0%) | ||||
QALYs | 5,598 | 5,498 | 99.48 | Dominant | |
Costs (€ thousand) | €6,346 | €1,348 | - €4,999 | ||
S7 | Only considering Acetate carbonate | ||||
QALYs | 4,643 | 4,713 | 69.54 | Dominant | |
Costs (€ thousand) | €4,906 | €1,324 | - €3,582 | ||
S8 | Only considering Calcium carbonate | ||||
QALYs | 4,511 | 4,590 | 79.02 | Dominant | |
Costs (€ thousand) | €5,223 | €1,025 | - €4,198 | ||
S9 | Dialysis mortality from Block 1998 | ||||
QALYs | 4,571 | 4,620 | 49.51 | Dominant | |
Costs (€ thousand) | €4,840 | €1,170 | -€3,670 | ||
S10 | Without utility decrement for vomiting | ||||
QALYs | 4,579 | 4,653 | 73.93 | Dominant | |
Costs (€ thousand) | €5,044 | 1,169 | - €3,875 | ||