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Table 2 Base case economic model input data assumptions

From: Exploratory cost-effectiveness analysis of cardiac resynchronization therapy with systematic device optimization vs. standard (non-systematic) optimization: a multinational economic evaluation

Model variable

Germany

France

Spain

Italy

UK

Tariff for CRT-P implantationa

€ 11.924

€ 9.412

€ 10,791

€ 8,921

£ 8,281

Actual cost of CRT

€ 12,326

€ 9,280

€ 11,121

€ 8,455

£ 6,474

Cost of CRT procedure

     

 CRT-P device incl. leads

€ 5,569

€ 5,816

€ 5,428

€ 3,950

£ 3,411

 Other costsb

€ 3,169

€ 1,654

NA

€ 718

£ 1,555

 Premium for sensor leadc

€ 2,000

€ 2,000

€ 2,000

€ 2,000

£ 1,665

Unit cost follow-up HF hospitalizationd

€ 2,328

€ 3,577

€ 3,364

€ 3,052

£ 3,411

Average monthly cost of optimal drug therapye

€ 59

€ 18

€ 18

€ 18

£ 22

Tariff for CRT optimization services

     

 Routine cardiology consultation

€ 28

€ 61

€ 45

€ 21

£ 62

 Consultation with echocardiographic control

€ 28

€ 96

€ 79

€ 52

£ 86

 Device optimization by echocardiography

€ 73

€ 96

€ 147

€ 52

£ 120

Actual costs for CRT optimization servicesf

     

 Routine cardiology consultation

€ 24

€ 28

€ 19

€ 17

£ 17

 Consultation with echocardiographic control

€ 62

€ 70

€ 48

€ 36

£ 43

 Device optimization by echocardiography

€ 147

€ 169

€ 115

€ 87

£ 101

Discount rate

     

 Costs

3.0 %

3.0 %

3.0 %

3.0 %

3.5 %

 Benefits

3.0 %

3.0 %

3.0 %

3.0 %

3.5 %

  1. aWeighted tariff taking into account the relative frequency of implantations by DRG severity category and corresponding tariffs (applies if more than one DRG for CRT is reported in the DRG catalogue)
  2. bE.g. cost for personnel involved in CRT implantation, diagnostic examinations, disposables/consumables, medication, overhead costs
  3. cAssumption as there is currently no information on the extra cost for the sensor lead available; this expense was applied to the systematic optimization group only and also taken into account (conservative approach) for the analysis performed from the perspective of the healthcare payer although the current DRG tariff for CRT would currently include this expense
  4. dPer stay
  5. eFor Germany based on reference [26]; for the UK based on reference [27]; for remaining countries based on own assumptions
  6. fComputed from the estimated duration of optimization service and hourly cost of personnel involved in the optimization procedures (CRT and/or echo specialist)