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Table 1 Unit costs

From: Cost analysis of glatiramer acetate versus interferon-β for relapsing-remitting multiple sclerosis in patients with spasticity: the Escala study

Treatment

Units/Dosage forms

Cost/Unit (2014 ex-factory price)

Cost/Unit −7.5%a (2014 ex-factory price)

Disease modifying treatment

   

 Glatiramer acetate

20 mg/ml, 28 prefilled syringes, 1 ml

781.25€

722.55€

 IFN-β 1a sc

44 μcg/0.5 ml, 4 cartridges, 1.5 ml

1,167.21€

1,079.76€

 IFN-β 1a im

30 μcg, 4 prefilled syringes, 0.5 ml

835.82€

773.13€

 IFN-β 1b sc

250 μcg/ml, 15 powder and solvent for injection, 1.2 ml

865.00€

800.13€

Spasticity treatment

   

 Baclofen

10 mg, 1 vial, 5 ml

19.83€

NA†

 Clonazepam

60 tablets, 2 mg

2.00€

 Diazepam

100 tablets, 5/10 mg

1.30€

 Lorazepam

20 tablets, 5 mg

2.00€

 Tetrazepam

30 tablets, 50 mg

2.83€

 Tizanidine

30 tablets, 2 mg

2.53€

 Gabapentin

90 capsules, 300 mg

5.93€

 Botulinum toxin

1 vial, 100 IU

159.12€

147.18€

Relapses cost/patient (direct and indirect costs included)

One episode

2,609.00€

NA

  1. aThe cost analysis is expressed in 2014 euros (€) and a discount of 7.5 % on treatment prices was applied as stipulated in Spanish law (Royal Decree 8/2010); †A price discount of 7.5 % was not applied since these are generic drugs
  2. im intramuscular, NA not applicable, sc subcutaneous