Table 4 Discounts by benefit categories and indication class (Orphan drugs)
From: Benefit assessment in Germany: implications for price discounts
Additional benefit: overall | |||||
Indication class by ICD-10 | n | Mean | Min | Max | SD |
Diseases of the respiratory system | 1 | 10.96 | 10.96 | 10.96 | – |
Diseases of the circulatory system | 3 | 22.31 | 20.72 | 25.49 | 2.75 |
Neoplasms | 16 | 19.59 | 9.00 | 29.78 | 5.82 |
Other | 1 | 24.50 | 24.50 | 24.50 | – |
Endocrine, nutritional and metabolic diseases | 6 | 12.43 | 1.00 | 25.31 | 10.17 |
Diseases of the digestive system | 2 | 20.21 | 14.87 | 25.54 | 7.54 |
Overall | 29 | 18.31 | 1.00 | 29.78 | 7.27 |
Size of target population (upper level) | 29 | 1896 | 11 | 7850 | 2583 |
Additional benefit: considerable | |||||
Indication class by ICD-10 | n | Mean | Min | Max | SD |
Neoplasms | 2 | 20.80 | 19.78 | 21.81 | 1.44 |
Endocrine, nutritional and metabolic diseases | 1 | 5.05 | 5.05 | 5.05 | – |
Overall | 3 | 15.55 | 5.05 | 21.81 | 9.15 |
Size of target population (upper level) | 3 | 2348 | 143 | 5000 | 2459 |
Additional benefit: minor | |||||
Indication class by ICD-10 | n | Mean | Min | Max | SD |
Diseases of the circulatory system | 3 | 22.31 | 20.72 | 25.49 | 2.75 |
Neoplasms | 3 | 21.55 | 13.85 | 25.81 | 6.68 |
Other | 1 | 24.50 | 24.50 | 24.50 | – |
Endocrine, nutritional and metabolic diseases | 5 | 13.91 | 1.00 | 25.31 | 10.62 |
Diseases of the digestive system | 1 | 25.54 | 25.54 | 25.54 | – |
Overall | 13 | 19.32 | 1.00 | 25.54 | 8.21 |
Size of target population (upper level) | 13 | 2167 | 11 | 7850 | 2924 |
Additional benefit: non-quantifiable | |||||
Indication class by ICD-10 | n | Mean | Min | Max | SD |
Diseases of the respiratory system | 1 | 10.96 | 10.96 | 10.96 | – |
Neoplasms | 11 | 18.84 | 9.00 | 29.78 | 6.29 |
Diseases of the digestive system | 1 | 14.87 | 14.87 | 14.87 | – |
Overall | 13 | 17.93 | 9.00 | 29.78 | 6.21 |
Size of target population (upper level) | 13 | 1521 | 25 | 7500 | 2393 |