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Table 7 Results of the univariate regressiona (N = 193)

From: Benefit assessment in Germany: implications for price discounts

Predictor (X)

n

Beta

SE

Coeff (β)

p-value

R2

Additional benefit

100

−0.041

0.019

−0.156

0.030*

0.024

 Major

1

−0.084

0.132

−0.046

0.527

0.002

 Considerable

29

−0.015

0.027

−0.042

0.564

0.002

 Minor

48

−0.014

0.022

−0.045

0.532

0.002

 Non-quantifiable

22

−0.052

0.030

−0.127

0.078

0.016

 No additional benefit

92

0.044

0.019

0.167

0.020*

0.028

 Less benefit (additional harm potential)

1

−0.130

0.132

−0.071

0.324

0.005

Orphan status

29

−0.043

0.026

−0.117

0.104

0.014

Indication per category

 Certain infectious and parasitic diseases

51

0.001

0.022

0.002

0.975

0.000

 Diseases of the blood and blood-forming organs

2

0.026

0.094

0.020

0.784

0.000

 Diseases of the circulatory system

14

0.035

0.036

0.070

0.332

0.005

 Diseases of the digestive system

6

0.056

0.054

0.075

0.303

0.006

 Diseases of the eye and adnexa

7

−0.026

0.051

−0.037

0.609

0.001

 Diseases of the genitourinary system

2

−0.022

0.094

−0.017

0.816

0.000

 Diseases of the musculoskeletal system and connective tissue

1

0.176

0.131

0.096

0.183

0.008

 Diseases of the nervous system

9

0.167

0.043

0.268

0.000**

0.072

 Diseases of the respiratory system

9

−0.095

0.044

−0.152

0.034*

0.023

 Diseases of the skin and subcutaneous tissue

1

0.209

0.131

0.114

0.113

0.013

 Endocrine, nutritional and metabolic diseases

24

−0.024

0.029

−0.060

0.403

0.004

 Mental and behavioral disorders

2

0.038

0.094

0.029

0.689

0.001

 Neoplasms

57

−0.028

0.021

−0.097

0.181

0.009

 Other

8

−0.013

0.048

−0.020

0.787

0.000

Number of ACT >1

83

0.016

0.019

0.059

0.418

0.003

Incorporated HRQoL-data

49

−0.036

0.022

−0.119

0.100

0.014

  1. Abbreviations: HRQoL health-related quality of life, Beta standardized coefficient, SE standard error, Coeff coefficient, R 2 coefficient of determination
  2. ** Significant at the 0.01 level
  3. * Significant at the 0.05 level
  4. a Dependent Variable (Y): price change (discount)