Table 1 Input parameters

cost inpatient surgery (DIS & ACLR)

3,605.09€

-

G-DRG catalogue

cost DIS (Ligamys)

1,284.00€

-

Mathys AG, Bettlach

cost monobloc removal (DIS)

398.85 €

2,190.83€

Eggli et al. (2016) [33], expert opinion, G-DRG catalogue

cost medical devices (ACLR)

532.00€

-

payer data

average costs of rehab per cycle

82.00€

-

payer data

cost medication (ACLR)

117.92€

-

official tariff (Lauer Taxe)

cost medication (DIS)

58.86€

-

official tariff (Lauer Taxe)

disutility for revision surgery

0.05

0–0.1

Mather et al. (2014) [6]

monobloc removal rate (DIS)

0.241

0.05

Henle et al. (2015) [11]

probability of revision surgery (DIS)

0.029

-

Henle et al. (2015) [11]

probability of revision surgery (ACLR)

0.025

0.0025–0.14

Janssen et al. (2012); Magnussen et al. (2010); Lind et al. (2012); Frobell et al. (2013) [1, 4, 15, 31]

days in hospital (DIS)

2

-

Henle et al. (2015) [11]

days in hospital (ACLR)

5

-

Geiger et al. (2013) [25]

discount rate

0.03

0–0.05%

german HTA guidelines [26]

number of prescriptions for rehab

2

-

payer data

hrQoL baseline (DIS)

0.85

beta dist. 0.85 +/- 0.09

study data on file

hrQoL baseline (ACLR)

0.80

beta dist. 0.80 +/- 0.11

Mather et al. (2014) [6]

hrQoL first 12 m (DIS)

0.79375

beta dist. 0.79375 +/- 0.1

study data on file

hrQoL first 12 m (ACLR)

0.79813

beta dist. 0.79813 +/- 0.11

Mather et al. (2014) [6]

hrQoL after revision (DIS)

lq_ACLR_norm

Assumption; equals the baseline hrQoL of ACLR because ACLR treatment is the revision therapy for DIS

hrQoL after revision (ACLR)

0.755

0.71–0.8

Lind/Menhert et al. (2012); Spindler et al. (2011); Lind/Lund et al. (2012); Wright et al.(2011) [15, 17, 27, 30]

time to revision surgery in months (ACLR)

21.6

9.6–33.6

Lind/Menhert et al. (2012) [15]

time to revision surgery in months (DIS)

11.1

3.5–24.3

Henle et al. (2015) [11]