From: Discrete-choice modelling of patient preferences for modes of drug administration
Variables | Definitions (Effects coding) |
---|---|
INTRAVENOUS | =1 if a drug is administered intravenously (1, 0, 0, −1) |
SUBCUTANEOUS | =1 if a drug is administered subcutaneously (0, 1, 0, −1) |
INTRAMUSCULAR | =1 if a drug is administered ntramuscularly (0, 0, 1, −1). The reference category (−1) is administration via needle-free routes |
DOSFREQ | Continuous variable referring to the number of unit administrations over a one year period for a single full course of treatment |
NONCLINICAL_SELF | =1 if a drug is self-administered in non-clinical settings (1, 0, −1) |
NONCLINICAL_SUPV | =1 if a drug is administered in non-clinical settings under the supervision of a qualified healthcare professional (0, 1, −1). The reference category (−1) is drug administration in clinical settings |
DDA_MODERATE1 | =1 if a given mode of administration is associated with moderate but manageable disruption to respondents’ daily activities (1, 0, 0, −1) |
DDA_MODERATE2 | =1 if a given mode of drug administration is associated with moderate disruptions to daily activities that a respondent cannot cope with (0, 1, 0, −1) |
DDA_SEVERE | =1 if a given mode of drug administration is associated with severe disruption to the respondent’s daily activities (0, 0, 1, −1). The reference category (−1) is a mode of administration that carries no risk of disruption to patients’ daily activities |
RAE_MODERATE | =1 if the risk of adverse events associated with a given mode of drug administration s moderate (1, 0, −1) |
RAE_SEVERE | =1 if the risk of adverse events associated with a given mode of drug administration is severe (0, 1, −1). The reference category (−1) is drug delivery that is associated with no risk of adverse events |
COST | Continuous variable indicating the time and travel costs borne by patients per unit administration |
A | Alternative-specific constant = 1 for drug option A (1, −1). The reference point, drug option B = −1 |
FEMALE | =1 if survey respondent is female (1, −1). The reference category (−1) are males |
RESPONDENTAGE | Continuous variable indicating the age of a survey respondent |
VOCATIONAL | =1 if the highest level of education attained by a respondent is vocational training (1, 0, −1) |
GCSEs_O + A | =1 if the highest level of education attained by a respondent is GCSEs O′ and A’ levels (0, 1, −1). The reference category (−1) are respondents with “higher education” |
EMPLOYED | =1 if respondent is employed (1, −1). The reference category (−1) are those who are currently unemployed |
INCOME_1 | =1 if respondent’s annual household income is under £15,000 (1, 0, 0, 0, −1) |
INCOME_2 | =1 if respondent’s annual household income is between £15,000 and £29,999 (0, 1, 0, 0, −1) |
INCOME_3 | =1 if respondent’s annual household income is between £30,000 and £49,999 (0, 0, 1, 0, −1) |
INCOME_4 | =1 if respondent’s annual household income is between £50,000 and £75,000 (0, 0, 0, 1, −1). The reference category (−1) are respondents with annual household income in excess of £75,000 |
PRIOR_ ILLNESS | =1 if a survey respondent had received medical treatment under the advice or guidance of a qualified health worker over the past year (1, −1). The reference category (−1) are those who remained healthy over the past year |