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Table 6 Health-related data for included studies

From: The cost-effectiveness of exercise-based cardiac rehabilitation: a systematic review of the characteristics and methodological quality of published literature

Author (Year)

Health Outcomes

Follow up frequency and extent of Health outcomes

Patient sample loss to follow up

Effectiveness Measure (Instrument)

Preference-based Outcome

Levin et al. (1991) [13]

Total cost during study period (cost-benefit analysis)

NR

82/147 (56%) of patients completed initial 3-months.

78/147 (53%) of patients completed year-1.

72/147 (49%) of patients completed year-2.

Note: figures given of CRPP arm

Total cost per patient

Not a preference-based outcome

Oldridge et al. (1993) [4]

HRQL

Baseline, 4, 8 and 12-months

NR

QALY (NR)

Time-trade off change score

Ades et al. (1997) [16]

Survival

N/A

N/A

Year of life saved

Not a preference-based outcome

Carlson et al. (2000) [18]

Cardiovascular health

Baseline and 6-months

At 6-months, 67/80 (84%)

Primary: maximal oxygen consumption, low-density lipoprotein cholesterol

Not a preference-based outcome

Hall et al. (2002) [15]

HRQL

Every week for 6-weeks, then 3, 6 and 12-months.

13 (9%) patients did not complete any questionnaires (adjusted sample size, n = 129)

At 3-months, 98/129 (76%) patient data

At 6-months, 101/129 (78%) patient data

At 12-months, 76/129 (59%) patient data

Return to normal activities and Quality of Life score (Health Measurement Questionnaire)

Not a preference-based outcome

Southard et al. (2003) [9]

Monetary equivalent for (costs of) cardiovascular events

Baseline and 6-months

At 6-months, 100 (96%) patient data

Health care costs

Not a preference-based outcome

Yu et al. (2004) [19]

HRQL

Phase 1 (baseline), phase 2, 3 and 4 (2-years)

At 2-yrs., data available for 204 (76%) patients.

QALY (SF-36)

Patient reported time trade off score

Briffa et al. (2005) [12]

HRQL

Baseline, 6 and 12-months

At 6-months, 109/113 (96%) patient data

At 12-months, 105/111 (95%) patient data

QALY (SF-36 and UBQ-H)

Preference-based utility based on UBQ-H questionnaire

Reid et al. (2005) [17]

Exercise, cardiac risk, HRQL, depression

Baseline, 3, 12 and 24-months

At 3-months, 344 (87.8%) patient data

At 12-months, 314 (80.1%) patient data

At 24-months, 252 (64.2%) patient data

Peak oxygen uptake, kilojoules of energy related to activity, HDL-C and TGs, cardiac events, Heart diseases HRQL (McNew instrument), generic HRQL (SF-36), Depressive symptoms (Centre for Epidemiological Studies Depression scale)

Not a preference-based outcome

Jolly et al. (2007) [11]

HRQL

6,12 and 24-months

At 6-months, 485 (93%) patient data

At 12-months, 475 (91.5%) patient data

At 24-months, 461 (89%) patient data

QALY (EQ-5D)

EQ-5D summary score based on UK value set tariff

Taylor et al. (2007) [10]

HRQL

Baseline, 3 and 9-months

At 9-months, data available for 48 (80%) and 32 (73%) of the home- and hospital-based groups respectively.

QALY (EQ-5D)

EQ-5D summary score based on UK value set tariff

Dendale et al. (2008) [14]

Monetary equivalent for (costs of) cardiovascular events

Two examinations in 6-month period, single examination annually thereafter

NR

Health care costs

Not a preference-based outcome

Huang et al. (2008) [21]

Survival

N/A

N/A

Year of life saved

Not a preference-based outcome

Papadakis et al. (2007) [2]

HRQL

3, 6, 12, 15 and 24-months.

At 2-yrs., data available for 307 (78%) patients.

QALY (NR)

Time trade off preference-based utility scores

Spronk et al. (2008) [20]

HRQL

N/A

N/A

QALY

Time-trade off preference-based utility score

  1. HRQL = Health related quality of life, NR = not reported, N/A = not applicable