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Table 2 Transition probabilities from the decision tree to the Markov model

From: Palivizumab in the prevention of severe respiratory syncytial virus infection in children with congenital heart disease; a novel cost-utility modeling study reflecting evidence-based clinical pathways in Spain

Parameter

Transition probability (Palivizumab and no prophylaxis)

Calculation (see Table 1 for efficacy inputs)

MA-RSV

 No sequelae, %

56.1

(1 − p Asthma ) × (1 − p AS )

 Asthma, %

6.4

p Asthma  × (1 − p AS )

 Allergic sensitization, %

33.6

(1 − p Asthma  ) × p AS

 Asthma and allergic sensitization, %

3.9

p Asthma  × p AS

RSV-H

 No sequelae, %

38.1

(1 − p Asthma ) × (1 − p AS )

 Asthma, %

18.4

p Asthma  × (1 − p AS )

 Allergic sensitization, %

29.3

(1 − p Asthma  ) × p AS

 Asthma and allergic sensitization, %

14.2

p Asthma  × p AS

  1. Abbreviations: RSV, respiratory syncytial virus; MA-RSV, medically attended RSV infection; AS, allergic sensitization; RSV-H, RSV infection resulting in hospitalization