|Study||Aim||Methods||Outcome measure||Findings||Notes||Quality assessment|
|Hay et al., (2010) ||To examine the links between exposure to maternal depression in pregnancy and antisocial outcomes in children.||
Longitudinal study of 120 families in Britain.|
Families were followed until the child was around 16 years.
|Incidence of arrests and DSM diagnoses.||Antenatal exposure to cigarette smoking did not predict antisocial outcomes for children.||Adjusted for a wide range of covariates||Moderate|
|Macleod et al., (2008) ||To estimate the prevalence of alcohol and tobacco use among children||Birth cohort study in England (n = 6895, 3410 male)||Measured self-reported use of tobacco and alcohol at age 10.||After adjusting for potential covariates no significant association was found between maternal smoking and child tobacco and alcohol use.||
Good range of covariates.|
10 years old likely too young for outcome measure
|Murray et al., (2010) ||To identify early predictors of conduct problems and crime||Large UK cohort study (n = 16,401) followed up to age 34 years||
Child conduct problems at age 10 measured using parent-rated Rutter A2 scale.|
Convictions were self-reported at ages 30 and 34 years.
|In fully adjusted models, maternal smoking during pregnancy was significantly associated with conduct problems at age 10 (partial OR = 1.8 [95% CI: 1.3-2.5] for girls; Partial OR = 1.7 [95% CI: 1.4-2.2] for boys) and convictions in adulthood (partial OR = 1.8 [95% CI: 1.2-2.7] for girls; partial OR = 1.4 [95% CI: 1.1-1.7] for boys).||Adjusted for a wide range of covariates||Strong|