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Table 4 Results of model analysis (deterministic and probabilistic sensitivity analysis)

From: Real-world cost-effectiveness of cetuximab in the third-line treatment of metastatic colorectal cancer based on patient chart review in the Netherlands

 

LY (95% CI)

QALY (95% CI)

Cost, € (95% CI)

Deterministic analysis (undiscounted)

 Cetuximab + BSC

0.61

0.48

37,146

 BSC

0.32

0.24

3678

 Incremental

0.29

0.25

33,468

 ICER

115,690

134,495

 

Deterministic analysis (discounted)

 Cetuximab + BSC

0.61

0.48

36,637

 BSC

0.32

0.23

3648

 Incremental

0.29

0.25

32,989

 ICER

114,907

133,527

 

PSA (undiscounted)

 Cetuximab + BSC

0.61 (0.57–0.64)

0.48 (0.45–0.51)

36,915 (26,773–48,716)

 BSC

0.32 (0.30–0.34)

0.24 (0.22–0.25)

3639 (2520–4982)

 Incremental

0.29 (0.25–0.33)

0.25 (0.21–0.28)

33,276 (22,720–45,027)

 ICER

116,030 (80,417–158,009)

134,777 (92,521–184,072)

 

PSA (discounted)

 Cetuximab + BSC

0.61 (057–0.64)

0.48 (0.45–0.51)

36,410 (26,407–48,053)

 BSC

0.32 (0.30–0.34)

0.24 (0.22–0.25)

3609 (2498–4942)

 Incremental

0.29 (0.24–0.33)

0.25 (0.21–0.28)

32,801 (22,394–44,397)

 ICER

115,248 (79,861–156,946)

133,812 (92,521–184,072)

 
  1. BSC best supportive care, ICER incremental cost-effectiveness ratio, LY life-year, PSA probabilistic sensitivity analysis, QALY quality-adjusted life-year