Table 1 Results of the sensitivity analysis for 9 parameters with a high degree of fluctuation and the discount factor, timeframe remaining lifetime, starting age 75 years old
Parameter | Variable | Minimum value | Delta costs * | Maximum value | Delta costs a | |
|---|---|---|---|---|---|---|
Base case, model timefram lifetime, starting age 75 years Discounted by 3% | M F | 147.67 € 113.93 € | ||||
pAF | Undetected AF in % of detected AF population (base case: 33%) | M F | 10% | 8.94 € −1.18 € | 70% | 365.67 € 294.82 € |
cStroke_ Factor | Scaling factor stroke costs 100% = base case | M F | 50% | 63.18 € 43.66 € | 150% | 232.15 € 184.20 € |
RSA_Factor | Scaling factor RSA compensation payments; base case: factor 1.0 | M F | 0.0 | 7.77 € 1,99 € | 1.25 | 182.64 € 141.91 € |
orStroke_AF_ reduction | Effectiveness of stroke prevention 0% - no effect; base case: 70% | M F | 40% | 74.20 € 52.11 € | 90% | 204.81 € 161.76 € |
AgeStart | Starting age of the population Base case: 75 years old | M F | 65 years old | 52.42 € 8.22 € | 85 years old | 156.65 € 126.67 € |
orStroke_AF_ NOATT | Increased stroke rate with AF without prevention; Base case: factor 4.2 | M F | 2.0 | 89.75 € 64.33 € | 5.0 | 163.29 € 127.32 € |
cTest_Factor | Scaling factor screening costs 100% = base case (€47.54 / €297.50) | M F | 50% | 155.34 € 119.88 € | 500% | 86.27 € 66.28 € |
orMortAF_base | Increased background mortality, AF subpop. 25% increase = base case | MF | 0% | 171.69 € 131.13 € | 75% | 113.86 € 89.36 € |
Discount rate | Discount factor 3% = base case | M F | 1% | 164.53 € 127.87 € | 5% | 132.34 € 101.26 € |