Comorbidities and HCV coinfection in the management of HIV+ patients: evidence from the Italian clinical practice

Garagiola, Elisabetta; Foglia, Emanuela; Ferrario, Lucrezia; Meraviglia, Paola; Tebini, Alessandro; Menzaghi, Barbara; Atzori, Chiara; Rizzardini, Giuliano; Bini, Teresa; D’Arminio Monforte, Antonella; Croce, Davide

doi:10.1186/s13561-020-00284-x

Health Economics Review

Table 8 Economic impact (mean total cost): differences across sub-groups of comorbidities

From: Comorbidities and HCV coinfection in the management of HIV+ patients: evidence from the Italian clinical practice

	The entire sample			HIV mono-infected patients			HIV/HCV co-infected patients
HCV Infection	Average Value	Standard Error	p-value	Average Value	Standard Error	p-value	Average Value	Standard Error	p-value
Absence of HCV infection	10,090.69 €	334.75 €	0.000	Not Applicable	Not Applicable	Not Applicable	Not Applicable	Not Applicable	Not Applicable
Presence of HCV infection	17,074.70 €	1,187.14 €	0.000	Not Applicable	Not Applicable	Not Applicable	Not Applicable	Not Applicable	Not Applicable
Cardiovascular disease	Average Value	Standard Error	p-value	Average Value	Standard Error	p-value	Average Value	Standard Error	p-value
Absence of cardiovascular disease	12,070.49 €	792.10 €	0.048	8,717.72 €	442.80 €	0.009	14,377.01 €	1,267.71 €	0.037
Presence of cardiovascular disease	14,404.40 €	871.29 €	0.048	10,643.30 €	429.75 €	0.009	19,005.54 €	1,813.91 €	0.037
Neurocognitive impairment	Average Value	Standard Error	p-value	Average Value	Standard Error	p-value	Average Value	Standard Error	p-value
Absence of neurocognitive impairment	14,518.94 €	800.07 €	0.000	10,425.92 €	395.75 €	0.042	18,884.83 €	1,554.33 €	0.000
Presence of neurocognitive impairment	10,271.29 €	301.04 €	0.000	8,709.13 €	497.84 €	0.042	11,513.49 €	308.11 €	0.000
HBV Infection	Average Value	Standard Error	p-value	Average Value	Standard Error	p-value	Average Value	Standard Error	p-value
Absence of HBV infection	13,164.39 €	643.60 €	0.153	10,121.96 €	376.05 €	0.831	15,960.67 €	1,164.25 €	0.035
Presence of HBV infection	16,571.34 €	2,276.63 €	0.153	9,926.26 €	698.56 €	0.831	28,944.94 €	5,772.21 €	0.035
Bone disease	Average Value	Standard Error	p-value	Average Value	Standard Error	p-value	Average Value	Standard Error	p-value
Absence of bone disease	14,089.24 €	83.74 €	0.043	9,878.89 €	316.44 €	0.028	21,076.62 €	2,064.49 €	0.000
Presence of bone disease	12,143.66 €	469.12 €	0.043	12,632.31 €	2,099.83 €	0.028	12,058.96 €	417.99 €	0.000
Renal Impairment	Average Value	Standard Error	p-value	Average Value	Standard Error	p-value	Average Value	Standard Error	p-value
Absence of renal impairment	13,749.50 €	666.56 €	0.012	10,099.74 €	352.08 €	0.922	17,297.56 €	1,238.65 €	0.384
Presence of renal impairment	10,858.28 €	909.77 €	0.012	9,972.35 €	1,025.99 €	0.922	12,275.78 €	1,685.48 €	0.384
Diabetes	Average Value	Standard Error	p-value	Average Value	Standard Error	p-value	Average Value	Standard Error	p-value
Absence of diabetes	12,859.43 €	577.95 €	0.045	9,884.66 €	340.45 €	0.029	16,137.97 €	1,124.92 €	0.035
Presence of diabetes	19,048.37 €	3,120.83 €	0.045	12,670.23 €	1,452.30 €	0.029	22,001.21 €	4,472.99 €	0.035

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ISSN: 2191-1991

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