Health economic evaluations comparing faecal microbiota transplantation with antibiotics for treatment of recurrent Clostridioides difficile infection: a systematic review

Table 1 Results of the quality assessment of health economic evaluations

Item	Konijeti et al., 2014 [24]	Varier et al., 2015 [25]	Lapointe-Shaw et al., 2016 [26]	Merlo et al., 2016 [27]	Baro et al., 2017 [28]	Luo et al., 2020 [29]	Abdali et al., 2020 [30]
Question 1. Research aim	Yes	Yes	Yes	No	Yes	Yes	Yes
Question 2. Alternatives	Yes	Yes	Yes	Yes	Yes	Yes	Yes
Question 3. Effectiveness	Cannot tell	Cannot tell	Cannot tell	Cannot tell	Cannot tell	Cannot tell	Cannot tell
Question 4. Identification of costs and consequences	No	No	Yes	Cannot tell	No	No	No
Question 5. Measurement of costs and consequences	Cannot tell	Cannot tell	Yes	Cannot tell	Yes	Cannot tell	Yes
Question 6. Valuation of costs and consequences	Cannot tell	Cannot tell	Yes	Cannot tell	Yes	Cannot tell	Yes
Question 7. Extrapolation and discounting	NA	NA	Yes	Yes	NA	NA	NA
Question 8. Results	Yes	Yes	Yes	Yes	Yes	No	Yes
Question 9. Sensitivity analyses	Yes	Yes	Yes	No	Yes	Yes	Yes
Question 10. Discussion	Cannot tell	Cannot tell	Yes	No	Cannot tell	Cannot tell	Yes

The items reported in the table are based on the main topic of each item in the checklist for assessing economic evaluations reported by Drummond et al., 2015 [16]. The answers reported in the table indicate the compliance with the checklist-item: yes (adequate method), no (not adequate method), cannot tell (unclear) or not applicable. The complete checklist can be accessed through the original source [16]. NA = not applicable