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Table 4 Drug treatment, drug-related adverse event and metastasis cost items: clinical practice, unit costs and total cost

From: Economic burden of lung cancer in Turkey: a cost of illness study from payer perspective

Drug treatments cost item

Prescription (%)

SCLC

NSCLC

Chemotherapeutics

 Adjuvant-Neoadjuvant

–

20

 Advanced first-line therapy

100

74

  Poor performance

25

25

 Advanced second-line therapy

45

20

 Advanced third-line therapy

10

10

Other drugs

SCLC

NSCLC

Total (€)

 Analgesics

85

85

243.74

 Steroids

45

45

11.16

 Bisphosphonates

20

20

648.96

 Nutrition (3-month)

100

100

320.07

 G-CSF

2.5

2.5

841.94

Per patient drug treatment cost (€)

SCLC

1,484.19

NSCLC

2,765.58

Adverse events cost item

Annual rate (%)

Unit cost (€)

Total (€)

SCLC

NSCLC

 Rash

2

2

90.5

1.81

 Febrile Neutropenia

4

4

5,019.9

200.79

 Anemia

50

50

144.3

72.16

 Nausea/Vomiting

100

100

77.6

77.60

 Diarrhea

15

15

29.99

5.40

 Constipation

70

70

18.4

12.89

 Pulmonary Toxicity

25

25

635.51

133.87

 Fatigue

75

75

194.16

145.62

 Hypoalbuminemia

10

10

281.67

28.16

 Neutropenia

6

6

983.77

59

 Deep Vein Thrombosis

10

10

586.19

58.62

 Infection

50

50

11.75

5.9

 Anorexia

50

50

364.5

182.23

 Thrombocytopenia

5

5

162.34

8

 Edema

10

10

26

2.60

Per patient drug-related adverse event cost (€)

999.57

Metastasis cost item

Annual rate (%)

Unit cost (€)

Total (€)

SCLC

NSCLC

Central Nervous System

diagnosis

23

23

1,811.06

93.72

follow up

40

40

1,811.06

93.72

Bone

32.5

32.5

1,253.87

407.51

Liver

12.5

12.5

4,058.71

507.34

Pleura

14.3

14.3

102.02

14.59

Kidney

15

15

1,252.42

21.29

Per patient metastasis cost (€)

1,516.40

  1. G-CSF Granulocyte- Colony Stimulating Factor