From: Economic burden of lung cancer in Turkey: a cost of illness study from payer perspective
Drug treatments cost item | Prescription (%) | ||||
SCLC | NSCLC | ||||
Chemotherapeutics | |||||
 Adjuvant-Neoadjuvant | – | 20 | |||
 Advanced first-line therapy | 100 | 74 | |||
  Poor performance | 25 | 25 | |||
 Advanced second-line therapy | 45 | 20 | |||
 Advanced third-line therapy | 10 | 10 | |||
Other drugs | SCLC | NSCLC | Total (€) | ||
 Analgesics | 85 | 85 | 243.74 | ||
 Steroids | 45 | 45 | 11.16 | ||
 Bisphosphonates | 20 | 20 | 648.96 | ||
 Nutrition (3-month) | 100 | 100 | 320.07 | ||
 G-CSF | 2.5 | 2.5 | 841.94 | ||
Per patient drug treatment cost (€) | SCLC | 1,484.19 | |||
NSCLC | 2,765.58 | ||||
Adverse events cost item | Annual rate (%) | Unit cost (€) | Total (€) | ||
SCLC | NSCLC | ||||
 Rash | 2 | 2 | 90.5 | 1.81 | |
 Febrile Neutropenia | 4 | 4 | 5,019.9 | 200.79 | |
 Anemia | 50 | 50 | 144.3 | 72.16 | |
 Nausea/Vomiting | 100 | 100 | 77.6 | 77.60 | |
 Diarrhea | 15 | 15 | 29.99 | 5.40 | |
 Constipation | 70 | 70 | 18.4 | 12.89 | |
 Pulmonary Toxicity | 25 | 25 | 635.51 | 133.87 | |
 Fatigue | 75 | 75 | 194.16 | 145.62 | |
 Hypoalbuminemia | 10 | 10 | 281.67 | 28.16 | |
 Neutropenia | 6 | 6 | 983.77 | 59 | |
 Deep Vein Thrombosis | 10 | 10 | 586.19 | 58.62 | |
 Infection | 50 | 50 | 11.75 | 5.9 | |
 Anorexia | 50 | 50 | 364.5 | 182.23 | |
 Thrombocytopenia | 5 | 5 | 162.34 | 8 | |
 Edema | 10 | 10 | 26 | 2.60 | |
Per patient drug-related adverse event cost (€) | 999.57 | ||||
Metastasis cost item | Annual rate (%) | Unit cost (€) | Total (€) | ||
SCLC | NSCLC | ||||
Central Nervous System | diagnosis | 23 | 23 | 1,811.06 | 93.72 |
follow up | 40 | 40 | 1,811.06 | 93.72 | |
Bone | 32.5 | 32.5 | 1,253.87 | 407.51 | |
Liver | 12.5 | 12.5 | 4,058.71 | 507.34 | |
Pleura | 14.3 | 14.3 | 102.02 | 14.59 | |
Kidney | 15 | 15 | 1,252.42 | 21.29 | |
Per patient metastasis cost (€) | 1,516.40 |