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Table 2 Selected articles and their relevant characteristics: year of publication, study design, country, year of data, perspective, and principal study aim

From: Cost analysis of chronic obstructive pulmonary disease (COPD): a systematic review

Article

Year of publication

Design

Country

Year of data

Perspective

Principal aim

Foo J et al. [6]

2016

Cross-sectional study

England

2012–2013

Society

To assess the economic impact of COPD based on an international survey of COPD patients.

Wacker M. E et al. [7]

2016

Cohort study

Germany

2010–2013

Society

To investigate COPD medical overuse, work absenteeism and resulting costs within the German COSYCONET cohort.

Chen W et al. [8]

2017

Cohort study

Canada

1996–2012

NHS*

To examine the impact of comorbidities on excess direct medical costs in patients with COPD.

Tachkov K et al. [9]

2017

Cohort study

Bulgaria

2014–2015

Patient

To calculate the economic and social burden of COPD in Bulgaria generated by lost productivity due to absence from work, early retirement, reduced productivity and DALYs.

Wacker M. E et al. [10]

2017

Cohort study

Germany

2010–2013

Society

To analyze the association of frequent comorbidities and common symptoms with the direct and indirect annual costs of COPD patients.

Quang Vo T et al. [11]

2018

Cohort study

Vietnam

2015–2017

NHS

To explore the direct medical costs associated with COPD and identify the key factors of disease management costs.

Lakiang T et al. [12]

2018

Cross-sectional study

India

2014–2015

Society

To study the economic impact (direct and indirect costs) of COPD patients receiving treatment in a tertiary hospital in South India.

Lisspers K et al. [13]

2018

Cohort study

Sweden

2000–2014

Society

To assess the direct and indirect costs of COPD in Sweden in relation to time, age and stage of disease.

Merino M et al. [14]

2018

Cohort study

Spain

2015

Society

To estimate the socioeconomic impact of COPD in Extremadura (Spain) in 2015.

Patel JG et al. [15]

2018

Cohort study

USA

2007–2010

Society

To measure the impact of COPD by calculating direct and indirect incremental costs.

Stafyla E et al. [16]

2018

Cohort study

Greece

2014–2015

Public decision maker

To estimate the annual cost of the COPD patient during the maintenance phase and to explore relationships between cost and disease severity.

Zhu B et al. [17]

2018

Systematic review

China

Until 2015

Society

To quantify the burden of COPD in China and to determine the risk factors for the disease.

Changhwan Kim M. D y col [18]

2019

Cohort study

Corea

From 2013

Society

To estimate the direct and indirect costs and inform the establishment of efficient strategies to reduce the financial burden of COPD in Korea.

Rehman A et al. [19]

2019

Systematic review

USA, Asia and Europe

Until 2019

NHS

To find the economic burden of COPD in the U.S., Europe and Asia and identify key cost drivers in the treatment of COPD patients.

Viinanen A et al. [20]

2019

Cohort study

Finland

2004–2015

NHS

To describe healthcare resource utilization and associated costs in COPD patients in Finland according to disease severity and blood eosinophil count.

Woo L et al. [21]

2019

Systematic review

Asia and Pacific

2000–2018

Society

To evaluate COPD cost studies and analyze cost comparisons between Asia-Pacific countries.

Iheanacho I et al. [22]

2020

Systematic review

Worldwide

2006–2016

Society

To highlight the economic burden associated with moderate-severe COPD and to investigate the key drivers of healthcare resource utilization, direct and indirect costs.

Rehman A et al. [23]

2020

Systematic review

Europe

Until 2019

Society

To estimate the economic impact of COPD and identify key cost drivers in the treatment of COPD patients in different European countries.

  1. *NHS: National Health System