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Table 2 Results of base case analysis

From: Cost-effectiveness analysis of Vaborem in Carbapenem-resistant Enterobacterales (CRE) -Klebsiella pneumoniae infections in Italy

 

Vaborem

BAT

Difference

Percentage change

Costs (€)

 

Total Costs

29,750.85

26,202.28

3548.57

13.5%

 Pharmacological treatment

2301.49

1485.23

816.26

55.0%

 Admission

3048.04

3048.04

0.00

0.0%

 Therapeutic failure

1841.64

3324.40

− 1482.76

−44.6%

 Chronic RRT

129.49

873.10

− 743.61

− 85.2%

 Long-term care

22,430.18

17,471.51

4958.68

28.4%

Clinical Effectiveness

 

Total QALY

1.786

1.403

0.384

27.4%

 Nephrotoxicity-free hospitalisation

0.033

0.031

0.002

7.2%

 Hospitalisation with nephrotoxicity

0.002

0.013

−0.012

− 88.3%

 Acute RRT

0.000

0.002

−0.002

−85.2%

 Chronic RRT (after 90 days)

0.002

0.013

−0.011

−85.2%

 After Hospital discharge

1.749

1.343

0.406

30.3%

Total LYs

2.253

1.778

0.475

26.7%

  1. BAT: best available therapy; LY: life years; QALY: quality assisted life years; RRT: renal replacement therapy