From: How innovation can be defined, evaluated and rewarded in health technology assessment
Solà-Morales et al. (2018) | Angelis & Kanavos (2017) | Ciani et al. (2016) | Garrison et al. (2017) | Mestre-Ferrandiz et al. (2012) | |
---|---|---|---|---|---|
Attributes related to therapeutic added value of technology, compared to relevant comparator | |||||
Therapeutic benefit | ✓ | ✗ | ✓ | ✗ | ✓ |
Attributes related to step-change | |||||
Breakthrough status | ✗ | ✗ | ✓ | ✗ | ✗ |
Attributes related to the underlying health condition of the patients & current care | |||||
Availability of existing intervention | ✓ | ✗ | ✗ | ✗ | ✓ |
Unmet need | ✓ | ✗ | ✗ | ✗ | ✓ |
Attributes related to safety | |||||
Safety | ✓ | ✗ | ✓ | ✗ | ✓ |
Attributes related to convenience | |||||
Patient usefulness (i.e. convenience) | ✓ | ✓ | ✓ | ✗ | ✓ |
Carer usefulness (i.e. convenience) | ✗ | ✗ | ✗ | ✗ | ✓ |
Administration | ✗ | ✗ | ✗ | ✗ | ✓ |
Attributes related to economic impact | |||||
Cost or budget impact | ✓ | ✗ | ✓ | ✗ | ✓ |
Impact on non-healthcare resources and productivity benefits | ✗ | ✗ | ✗ | ✗ | ✓ |
Attributes related to evidence base | |||||
Strength of clinical evidence | ✓ | ✗ | ✗ | ✗ | ✗ |
Learning curve | ✗ | ✗ | ✓ | ✗ | ✗ |
Attributes related to R&D and impact on future innovation pipeline (dynamic effects) | |||||
Novelty | ✓ | ✓ | ✗ | ✗ | ✗ |
Spill-over effects | ✗ | ✓ | ✗ | ✓ | ✗ |
Real option value | ✗ | ✗ | ✗ | ✓ | ✗ |