Table 1 Efficacy parameters: Screening and OAC Efficacy *
Category | base case | Description |
|---|---|---|
Screening | ||
 Undetected AF in % detected AF | 0.33 | Assumption (prevention, 1/3 ratio undetected AF to detectedAF) |
 Sensitivity Preventicus screening | 0.92 | from DETECT AF [29] |
 Specificity Preventicus screening | 0.99 | from DETECT AF [29] |
 Positively validated screening results (after Holter ECG) | 0.85 | Adoption acc. to Wachter et.al [38]. |
OAC Efficacy | ||
 Increased stroke rate with AF without prevention | 4.20 | mean: Wolf et.al [39]. SD: assumption |
 Reduction of stroke rate through prevention ** | 0.70 | |