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Table 3 Utility values for all health status of metastatic pancreas cancer from cTTO and VAS

From: Health state utility values for metastatic pancreatic cancer using a composite time trade-off based on the vignette-based approach in Japan

Health status

AE grade

cTTO

VAS

N

AVG

STE

N

AVG

STE

SD (reference)

–

201

0.634

0.024

105

0.468

0.019

SD + neutropenia

G1/2

201

0.649

0.026

105

0.438

0.019

SD + neutropenia

G3/4

105

0.514

0.042

105

0.346

0.019

SD + FN

G3/4

201

0.323

0.035

105

0.201

0.017

SD + diarrhea

G1/2

105

0.500

0.042

105

0.296

0.018

SD + diarrhea

G3/4

201

0.306

0.039

105

0.189

0.017

SD + vomiting

G1/2

201

0.422

0.035

105

0.299

0.018

SD + vomiting

G3/4

105

0.242

0.057

105

0.193

0.016

SD + neuropathy

G1/2

105

0.541

0.039

105

0.331

0.019

SD + neuropathy

G3/4

201

0.370

0.037

105

0.251

0.018

PD

–

201

-0.119

0.040

105

0.112

0.020

Myself (VAS score)

–

–

–

–

–

0.891

0.010

Death (VAS score)

–

–

–

–

–

0.128

0.011

  1. SD Stable disease, PD Progressive disease, cTTO Composite time trade-off, VAS Visual analog scale, AE Adverse event, FN Febrile neutropenia, AVG Average, STE Standard error, G Grade