From: The costs associated with stroke care continuum: a systematic review
First Author Year of publication Country | Objectives | Methods | Results | |||
---|---|---|---|---|---|---|
Design and GRADE LEVEL[32] | Participants | Instruments | Calculated stroke costs | |||
Alvarez-Sabin, 2013 (Spain) [44] | To find the cost of stroke in Spain | Epidemiological, observational, prospective, multicenter study 2 + GRADE | 321 patients | Sociodemographic, clinical, and economic data | Direct costs Indirect costs | Total average cost per patient/year was €27,711. Direct healthcare costs €849 patient/year and non-healthcare costs to an average of €18,643patient/year. Productivity loss costs per patient/year were €276 |
Van Eeden, 2015 (Netherlands) [45] | Explore over 1 year poststroke the societal costs, changes in costs and quality of life (QoL) and the relation between costs and QoL | Epidemiological, observational, prospective, multicenter study 2 + GRADE | 395 patients | Cost-of-illness (in Euros) and QoL (in utilities) of a disease | Direct costs Indirect costs | Indirect cost = €11,416 Direct cost = €18,068 Total societal costs for 1 year poststroke were €29 484 |
Xu, 2018 (UK), [46] | To estimate patient-level health and social care costs of stroke for all patients admitted to hospital with stroke in UK | Epidemiological, observational Retrospective Health economic simulation 2 + GRADE | 111,846 patients | Health Care Costs Productivity Costs | Direct costs Indirect costs | The estimated stroke cost varied widely according to patient characteristics, ranging from €8149 to €49,922 at one year and €21,259 to €119,464 at five years |
Benjamin. 2019 (EEUU) [4] | To estimate the cost of Cardio Vascular Diseases and risk factors | Statistical update 2 + GRADE | 18,462 patients | Health interview surveys | Direct costs Indirect costs | Direct care €6673 /patient/year Post ictus Care €9412/patient/year |
Luengo-Fernandez. 2020 (UK) [2] | To provide an estimate of the overall economic costs of stroke for all 28 countries of the EU | Population-based cost analysis 2 + GRADE | 1,5 million patients 32 European countries | Population-based cost analysis | Direct costs Indirect costs | Health Care: €17,728 /patient/year Social Care: €3165/patient/year Productivity costs: €8336/ patient/year Informal care costs: €10,508/ patient/year Total costs: €39,736,66 /patient/year |
Patel A, 2020 (UK) [47] | To estimate 2014/2015 annual cost from a societal perspective | Epidemiological retrospective study 2 + GRADE | 331 patients | Annual mean cost per person and aggregate UK cost of stroke for individuals aged ≥ 40 Health and social costs | Direct costs Indirect costs | Mean cost of new-onset stroke is €61,665 (95% CI €57,109-€66,220) in the first year after stroke and €33,648 (€27,477-€39,819) in subsequent years |
Rochmah TN, 2021 Indonesia [48] | To analyze the burden of stroke: analyzing the average length of hospitalization, and the magnitude of economic losses due to stroke | Systematic review 1 + GRADE | 13 articles | Cost of illness studies that assess burden of stroke in primary and referral healthcare (hospital-based) Direct and indirect costs | Direct costs Indirect costs | The economic burden of stroke disease based on cost of illness method, which is approximately equal to € 1478- €265,613 (direct costs 86.2%, and indirect costs 13.8%) |
Stefan Strilciuc, 2021 Romania[49] | To compile the results of existing studies on the economic burden of stroke, | Systematic review 1 + GRADE | forty-six articles published in twenty-three countries between 1994 and 2019 | Across all cost perspectives | Overall costs | Costs in the per patient per year category varied from €103,578 in South Korea (for hemorrhagic stroke) to €610 in Singapore |